Exposures of Concern
| "We know of relatively few chemicals
that have adverse effects on reproduction, but we are completely
ignorant of the potential reproductive toxicity of more than
90% of (the tens of thousands of) industrial chemicals to which
people are exposed."5 |
Much of the knowledge of environmental effects on reproductive
outcome stems from studies of acute toxic exposures, frequently
in the occupational setting. Another set of evidence showing
adverse reproductive effects comes exclusively from experimental
and wildlife studies of animals exposed to environmental pollutants.
Our understanding of the impact on human reproduction of chronic
low-level exposure to various environmental toxicants is woefully
incomplete. Researchers suggest, however, that since we are exposed
throughout our lifetimes to numerous substances that have demonstrated
reproductive effects in animals, it is reasonable to assume that
human reproductive health is being or may be compromised.6
Environmental Toxicants
Some of the environmental factors associated with reproductive
toxicity include metals such as lead, mercury
and cadmium, organic solvents such as toluene and ethylene glycol
ethers, and pesticides and endocrine disruptors such as PCBs, dioxin
and phthalates, etc. The known or speculated effects of these toxicants
are considered according the developmental stage of the reproductive
system.
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