Prevention
In the case of environmental dermatoses, once a diagnosis is certain
and treatment rendered, personal protection, avoidance and hygiene
are strategies to reduce the risk of such afflictions in the future,
especially if they represent the immune-mediated types of conditions.
Patient education and awareness is another important strategy to
prevention.
UV Exposure
Probably the single most important and comprehensive area of prevention
education currently concerns UVR. Because of the well-recognized
role of UV exposure in the pathogenesis of skin cancers and the
long latency period, it is important to stress preventive measures
as early as possible to parents of young patients.65,66
There is a great wealth of information on preventing
skin cancers.
Avoidance of exposure is the most important means of prevention.
Peak exposure time for UV rays is between 10 a.m. and 3 p.m., so
one approach is to minimize outdoor activities during this time.67
One figure cites that the UVR level is ten times greater at noon
than it is at times three hours earlier or later than noon.68
A useful rule advises that “if your shadow is shorter than you,
the risk of sunburn is substantial.”69
UV radiation varies seasonally in the northern hemisphere with
the highest exposure in June and July in Canada. The UV
index is a summary calculation that incorporates several factors
to estimate the intensity of UV light and the consequent time to
produce a sunburn in those who are of skin
type II. Environment Canada provides forecasts
of the daily ultraviolet (UV) indices for select Canadian cities.
During summer months, most media will report daily values for the
UV index. Parents and caregivers of young children should be aware
of such reports of the UV index.
Other practices that may reduce exposure are the use of appropriate
clothing and sunscreen
(sun protection factor of at least 15). Wide-brimmed hats and clothing
made of relatively opaque material provide significant protection
from UVR exposure. It is clear that our knowledge of the efficacy
of sunscreens is still evolving. Sunscreens are designed to absorb
UV radiation and to prevent erythema. Early studies state that use
of suncreen in childhood will significantly reduce the chances of
developing NMSC.70
A recent review suggests, however, that there is some question
as to whether sunscreens prevent cell photodamage and molecular
changes that appear to result from suberythemal doses of
UVR, or protect from exposure to UVA radiation. Recent experimental
research has also demonstrated that several of the most common chemicals
found in sunscreens display estrogenic activity.71
There remain, therefore, some questions surrounding the true efficacy
of sunscreens in preventing skin malignancies.72
There is also controversy over whether it is appropriate to apply
sunscreen to infants under six months of age because of the immaturity
of both the infant’s skin and metabolic capacities.73 As
a rule, it is best to ensure that infants under six months are not
directly exposed to the sun because their smaller body size renders
them predisposed to overheating. Infants should also have adequate
protection with clothing or screens that will block UVR.
The above precautions also hold for preventing excess exposure
of children in the day-care and school settings. Parents should
be explicit in expressing to caregivers, teachers and their older
children how best to protect their child from exposure to UV rays.
There are a number of resources that can
assist them in this vein. We must also not overlook the fact that
teens, who are more autonomous, may have even greater opportunity
for excess exposure to UVR through work and recreational activities.
Data on fair-skinned individuals living in Northern Europe indicate
that the risk at age 70 of NMSC in someone who worked indoors and
did not sunbathe is about 2 to 3%. Not surprisingly, an outdoor
worker who did not sunbathe has a threefold higher risk (7.4 to
11.1%) of NMSC. However, even someone who worked indoors but sunbathed
for about two weeks of the year has a comparable and even slightly
higher risk of developing NMSC as the non-sunbathing outdoor worker.
|
Exposure Situation
|
Risk at Age 70
(%)
|
|
Indoor worker, no sunbathing
|
2 – 3
|
|
Outdoor worker, no sunbathing
|
7.4 – 11.1
|
|
Indoor worker, sunbathing 2 wks/yr
|
10 - 15
|
|
Outdoor worker, sunbathing 2 wks/yr
|
37 – 55.5
|
|
Indoor worker, sunbathing 4 wks/yr
|
20 – 60
|
|
Outdoor worker, sunbathing 4 wks/yr
|
74 - 100
|
Risks of nonmelanoma skin cancer (NMSC) for various
exposure situations.74
Primary Prevention
Because of predictions that reductions in the atmospheric ozone
layer are likely to lead to much higher average exposure in current
and future generations, enhancing the public’s awareness of primary
prevention strategies is now even more important. The 1987 Montreal
Protocol on Substances that Deplete the Ozone Layer was an international
agreement that has called for a total elimination of ozone-depleting
substances by 2005.
Developed nations have made efficient strides toward reducing consumption
and emissions of such substances, undoubtedly averting many millions
of cases of skin cancer and eye cataracts. However, there is still
concern as to how effectively this phasing out can be accomplished
in some developing nations.75
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